Dr. George Medeiros, a brilliant scientist, is badly disfigured when his wife takes a lover and plans to murder him. After months in the hospital, he returns with nothing in mind but revenge.
While out for a walk in the countryside, Marina and Juvenal stop to take some pictures in front of an old woman’s house. Annoyed, the old woman turns out to be a witch and casts a curse on the young couple in the form of a wound that feeds on raw flesh.
A psychiatric doctor driven to insanity by nightmare visions of Zé do Caixão trying to steal his wife is helped by colleagues who enlist creator José Mojica Marins to convince the patient that he does not exist.