While attending the birth of Isabel, the wife of foreigner Felipe, Mama Santos predicts that "something terrible is going to happen in the town." From this omen, calamities will torment the locals.
A mechanic takes his family to a car race and a series of events occur which brings problems, betrayals, violence and the unexpected death of an elderly person.
Mónica, the manager and wife of singer Álex, plans a publicity stunt that goes awry. When her husband shoots a rival singer with a gun supposedly filled with blanks, the singer is killed with live ammo. Álex and Mónica then goes into hiding while trying to find out who set them up.
Regina, who lives with her son Daniel, loses her teaching job because his illegitimacy. She opens a sewing shop and keeps her child away from people. The movie narrates the dramatic relationship between a mother, her illegitimate child and the puritanical society around them.
Teresa is married to Filogonio, a man who suffers from pain in his legs, which prevents him from walking, so she decides to make a religious vow and travels to the sanctuary of the Lord of Chalma to ask for a miracle to cure her husband.